Header bg
  • Users Online: 173
  • Print this page
  • Email this page
Header bg
ORIGINAL ARTICLE
Year : 2020  |  Volume : 4  |  Issue : 3  |  Page : 104-108

Correlation of red cell distribution width and serum lactate levels in critically ill pediatric patients


1 Department of Child Health, Udayana University, Denpasar, Bali, Indonesia
2 Department of Anesthesiology and Intensive Care, Udayana University, Denpasar, Bali, Indonesia

Correspondence Address:
Dr. I Nyoman Budi Hartawan
Department of Child Health, Udayana University, JL, PB Sudirman, Denpasar 80232, Bali
Indonesia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/BJOA.BJOA_28_20

Rights and Permissions

Background: Blood lactate concentration has been widely used as a marker of altered tissue perfusion. An increase in lactate concentration to >1.5 mEq/L is associated with a higher mortality rate. Red cell distribution width (RDW) measures variability in red blood cell size. The purpose of this research is to see the correlation between lactate levels and RDW. Patients and Methods: We performed a cross-sectional study to assess the correlation between blood lactate concentration and RDW in critically ill children admitted to the pediatric intensive care unit (PICU) from October 2018 until February 2019. Blood lactate and RDW were taken during the first 24 h of admission. Data were obtained from the medical report. The association between RDW and lactate was determined using Spearman's correlation test. Results: There were forty patients enrolled in this study with a median age of 27 months (ranged from 2 months to 17 years), with an equal proportion of male and female. The median PICU length of stay was 7.5 days, with a mortality rate of 42.5%. The most common underlying disease was pneumonia (35%), followed by sepsis (17.5%) and meningitis (10%). The median lactate level was significantly higher in the nonsurvivor group compared to the survivor group (P = 0.002). The median RDW was also higher in the nonsurvivor group (P = 0.001). There is a moderate correlation between RDW and lactate (r = 0.532, P < 0.001). Conclusion: There was a moderate and significant correlation between RDW and serum lactate level in critically ill pediatric patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed146    
    Printed15    
    Emailed0    
    PDF Downloaded16    
    Comments [Add]    

Recommend this journal